An intermediate in the biosynthesis of polyphenylalanine directed by synthetic template RNA.

An Intermediate in the Biosynthesis of Polyphenylalanine Directed by Synthetic Template Rna By

The initial phase in the polyuridylic acid-directed polymerization of phenylalanine.

The ribosome-polyuridylic acid-phenylalanyl-soluble ribonucleic acid complex has been shown to be an intermediate in the synthesis of polyphenylalanine. About half of the phenylalanine incorporated into polypeptide from the complex was located in the N-terminus. The formation of this ribosomal complex with phenylalanyl-soluble ribonucleic acid is rate-limiting in the synthesis of polyphenylalan...

Antibacterial nitroacridine, Nitroakridin 3582: binding to nucleic acids in vitro and effects on selected cell-free model systems of macromolecular biosynthesis.

Nitroakridin 3582 (NA) formed complexes with native deoxyribonucleic acid (DNA) and with transfer ribonucleic acid (tRNA) species from Escherichia coli. Spectrophotometric titrations of NA with these nucleic acids produced numerical results from which nonlinear adsorption isotherms were derived. These curves indicated the existence of more than one class of binding sites on the polymers to whic...

A Facile and Green Biosynthesis of Silver Nanostructures by Aqueous Extract of Suaeda Acuminata after Microwave Assisted Extraction

In the present study, a simple, efficient and fast synthetic strategy was reported for the green biosynthesis of silver nanostructures (i.e. nanoroads and nanoparticles) by the extract of Suaeda Acuminata plant, without any catalyst, template or surfactant. Aqueous extracts were obtained by maceration and microwave assisted extraction (MAE) methods. In MAE procedure, the effec...

Protein synthesis by single ribosomes.

The ribosome is universally responsible for synthesizing proteins by translating the genetic code transcribed in mRNA into an amino acid sequence. Ribosomes use cellular accessory proteins, soluble transfer RNAs, and metabolic energy to accomplish the initiation, elongation, and termination of peptide synthesis. In translocating processively along the mRNA template during the elongation cycle, ...